KERSETİN/QUERCETIN (PowerPoint Sunum)

KAYNAKLAR

1-FLAVONOİDLER -Guliyev Vahid Bilaloğlu ve Mansur Harmandar

2-Wikipedia:Rutin

3-Comalada, M., Camuesco, D., Sierra, S., Ballester, I., Xaus, J., Gálvez, J., & Zarzuelo, A. (2005). In vivo quercitrin anti‐inflammatory effect involves release of quercetin, which inhibits inflammation through down‐regulation of the NF‐κB pathway. European journal of immunology, 35(2), 584-592.

4-Galvez, J., Crespo, M. E., Jimenez, J., Suarez, A., & Zarzuelo, A. (1993). Antidiarrhoeic activity of quercitrin in mice and rats. Journal of pharmacy and pharmacology, 45(2), 157-159.

5-Kim, Y., Narayanan, S., & Chang, K. O. (2010). Inhibition of influenza virus replication by plant-derived isoquercetin. Antiviral research, 88(2), 227-235.

6-Zhang, R., Yao, Y., Wang, Y., & Ren, G. (2011). Antidiabetic activity of isoquercetin in diabetic KK-A y mice. Nutrition & metabolism, 8(1), 85.

7-HUANG, Z. M. (2007). In vivo and in vitro antiviral activity of hyperoside extracted from Abelmoschus manihot (L) medik. Acta Pharmacologica Sinica, 28(3), 404-409.

8-Liu, Z., Tao, X., Zhang, C., Lu, Y., & Wei, D. (2005). Protective effects of hyperoside (quercetin-3-o-galactoside) to PC12 cells against cytotoxicity induced by hydrogen peroxide and tert-butyl hydroperoxide. Biomedicine & pharmacotherapy, 59(9), 481-490.

9-Li, W., Liu, M., Xu, Y. F., Feng, Y., Che, J. P., Wang, G. C., & Zheng, J. H. (2014). Combination of quercetin and hyperoside has anticancer effects on renal cancer cells through inhibition of oncogenic microRNA-27a. Oncology reports, 31(1), 117-124.

10-Wikipedia: Spiraeoside

11-Wikipedia:Troxerutin

12-Kelly, G. S. (2011). Quercetin. Altern. Med. Rev, 16(2), 172-194. ISO 690

13-Wiczkowski, W., Romaszko, J., Bucinski, A., Szawara-Nowak, D., Honke, J., Zielinski, H., & Piskula, M. K. (2008). Quercetin from shallots (Allium cepa L. var. aggregatum) is more bioavailable than its glucosides. The Journal of nutrition, 138(5), 885-888.

14-Mitchell, A. E., Hong, Y. J., Koh, E., Barrett, D. M., Bryant, D. E., Denison, R. F., & Kaffka, S. (2007). Ten-year comparison of the influence of organic and conventional crop management practices on the content of flavonoids in tomatoes. Journal of Agricultural and Food Chemistry, 55(15), 6154-6159.

15-Walle, T., Browning, A. M., Steed, L. L., Reed, S. G., & Walle, U. K. (2005). Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans. The Journal of Nutrition, 135(1), 48-52.

16-PDR for Nutritional Supplements

17-Crespy, V., Morand, C., Besson, C., Manach, C., Demigne, C., & Remesy, C. (2002). Quercetin, but not its glycosides, is absorbed from the rat stomach. Journal of agricultural and food chemistry, 50(3), 618-621.

18-Hollman, P. C., de Vries, J. H., van Leeuwen, S. D., Mengelers, M. J., & Katan, M. B. (1995). Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. The American journal of clinical nutrition, 62(6), 1276-1282.

19-McAnlis, G. T., McEneny, J., Pearce, J., & Young, I. S. (1999). Absorption and antioxidant effects of quercetin from onions, in man. European Journal of Clinical Nutrition, 53(2), 92-96.

20-Kyle, J. A., Morrice, P. C., McNeill, G., & Duthie, G. G. (2007). Effects of infusion time and addition of milk on content and absorption of polyphenols from black tea. Journal of Agricultural and Food Chemistry, 55(12), 4889-4894.

21-Hollman, P. C., Van Het Hof, K. H., Tijburg, L. B., & Katan, M. B. (2001). Addition of milk does not affect the absorption of flavonols from tea in man. Free radical research, 34(3), 297-300.

22-Lesser, S., Cermak, R., & Wolffram, S. (2004). Bioavailability of quercetin in pigs is influenced by the dietary fat content. The Journal of nutrition, 134(6), 1508-1511.

23-de Boer, V. C., Dihal, A. A., van der Woude, H., Arts, I. C., Wolffram, S., Alink, G. M., … & Hollman, P. C. (2005). Tissue distribution of quercetin in rats and pigs. The Journal of nutrition, 135(7), 1718-1725.

24-Bieger, J., Cermak, R., Blank, R., de Boer, V. C., Hollman, P. C., Kamphues, J., & Wolffram, S. (2008). Tissue distribution of quercetin in pigs after long-term dietary supplementation. The Journal of Nutrition, 138(8), 1417-1420.

25-Paulke, A., Nöldner, M., Schubert-Zsilavecz, M., & Wurglics, M. (2008). St. John’s wort flavonoids and their metabolites show antidepressant activity and accumulate in brain after multiple oral doses. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 63(4), 296-302.

26-Bronner, C., & Landry, Y. (1985). Kinetics of the inhibitory effect of flavonoids on histamine secretion from mast cells. Inflammation Research, 16(3), 147-151.

27-Joskova, M., Franova, S., & Sadlonova, V. (2011). Acute bronchodilator effect of quercetin in experimental allergic asthma. Bratisl Lek Listy, 112(1), 9-12.

28-Moon, H., Choi, H. H., Lee, J. Y., Moon, H. J., Sim, S. S., & Kim, C. J. (2008). Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs. Archives of pharmacal research, 31(6), 771.

29-Kawai, M., Hirano, T., Arimitsu, J., Higa, S., Kuwahara, Y., Hagihara, K., … & Kai, T. (2009). Effect of enzymatically modified isoquercitrin, a flavonoid, on symptoms of Japanese cedar pollinosis: a randomized double-blind placebo-controlled trial. International archives of allergy and immunology, 149(4), 359-368.

30-Aalinkeel, R., Bindukumar, B., Reynolds, J. L., Sykes, D. E., Mahajan, S. D., Chadha, K. C., & Schwartz, S. A. (2008). The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down‐regulating the expression of heat shock protein 90. The Prostate, 68(16), 1773-1789.

31-Castillo, M. H., Perkins, E., Campbell, J. H., Doerr, R., Hassett, J. M., Kandaswami, C., & Middleton, E. (1989). The effects of the bioflavonoid quercetin on squamous cell carcinoma of head and neck origin. The American journal of surgery, 158(4), 351-355.

32-Yang, K., Lamprecht, S. A., Liu, Y., Shinozaki, H., Fan, K., Leung, D., … & Lipkin, M. (2000). Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon. Carcinogenesis, 21(9), 1655-1660.

33-Hubbard, G. P., Wolffram, S., Lovegrove, J. A., & Gibbins, J. M. (2004). Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen‐stimulated platelet activation pathway in humans. Journal of Thrombosis and Haemostasis, 2(12), 2138-2145.

34-Hertog, M. G., Feskens, E. J., Kromhout, D., Hollman, P. C. H., & Katan, M. B. (1993). Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. The Lancet, 342(8878), 1007-1011.

35-Chaudhry, P. S., Cabrera, J., Juliani, H. R., & Varma, S. D. (1983). Inhibition of human lens aldose reductase by flavonoids, sulindac and indomethacin. Biochemical pharmacology, 32(13), 1995-1998.

36-Adewole, S. O., Caxton-Martins, E. A., & Ojewole, J. A. (2007). Protective effect of quercetin on the morphology of pancreatic β-cells of streptozotocin-treated diabetic rats. African Journal of Traditional, Complementary and Alternative Medicines, 4(1), 64-74.

37-Youl, E., Bardy, G., Magous, R., Cros, G., Sejalon, F., Virsolvy, A., … & Bataille, D. (2010). Quercetin potentiates insulin secretion and protects INS‐1 pancreatic β‐cells against oxidative damage via the ERK1/2 pathway. British journal of pharmacology, 161(4), 799-814.

38-Anjaneyulu, M., & Chopra, K. (2004). Quercetin attenuates thermal hyperalgesia and cold allodynia in STZ-induced diabetic rats.

39-Anjaneyulu, M., & Chopra, K. (2003). Quercetin, a bioflavonoid, attenuates thermal hyperalgesia in a mouse model of diabetic neuropathic pain. Progress in neuro-psychopharmacology and biological psychiatry, 27(6), 1001-1005.

40-Valensi, P., Le Devehat, C., Richard, J. L., Farez, C., Khodabandehlou, T., Rosenbloom, R. A., & LeFante, C. (2005). A multicenter, double-blind, safety study of QR-333 for the treatment of symptomatic diabetic peripheral neuropathy: a preliminary report. Journal of Diabetes and its Complications, 19(5), 247-253.

41-De La Lastra, C. A., Martin, M. J., & Motilva, V. (1994). Antiulcer and gastroprotective effects of quercetin: a gross and histologic study. Pharmacology, 48(1), 56-62.

42-Suzuki, Y., Ishihara, M., Segami, T., & Ito, M. (2001). Anti-ulcer effects of antioxidants, quercetin, α-tocopherol, nifedipine and tetracycline in rats. The Japanese Journal of Pharmacology, 78(4), 435-441.

43-Hamdy, A. A., & Ibrahem, M. A. (2010). Management of aphthous ulceration with topical quercetin: a randomized clinical trial. J Contemp Dent Pract, 11(4), E009-16.

44-Perez-Vizcaino, F., Duarte, J., Jimenez, R., Santos-Buelga, C., & Osuna, A. (2009). Antihypertensive effects of the flavonoid quercetin. Pharmacological Reports, 61(1), 67-75.

45-Conquer, J. A., Maiani, G., Azzini, E., Raguzzini, A., & Holub, B. J. (1998). Supplementation with quercetin markedly increases plasma quercetin concentration without effect on selected risk factors for heart disease in healthy subjects. The Journal of nutrition, 128(3), 593-597.

46-Edwards, R. L., Lyon, T., Litwin, S. E., Rabovsky, A., Symons, J. D., & Jalili, T. (2007). Quercetin reduces blood pressure in hypertensive subjects. The Journal of nutrition, 137(11), 2405-2411.

47-Gonzalez, O., Fontanes, V., Raychaudhuri, S., Loo, R., Loo, J., Arumugaswami, V., … & French, S. W. (2009). The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production. Hepatology, 50(6), 1756-1764.

48-Morikawa, K., Nonaka, M., Narahara, M., Torii, I., Kawaguchi, K., Yoshikawa, T., … & Morikawa, S. (2003). Inhibitory effect of quercetin on carrageenan-induced inflammation in rats. Life Sciences, 74(6), 709-721.

49-Stewart, L. K., Soileau, J. L., Ribnicky, D., Wang, Z. Q., Raskin, I., Poulev, A., … & Gettys, T. W. (2008). Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet. Metabolism, 57, S39-S46.

50-Filho, A. W., Filho, V. C., Olinger, L., & de Souza, M. M. (2008). Quercetin: further investigation of its antinociceptive properties and mechanisms of action. Archives of pharmacal research, 31(6), 713-721.

51-Valerio, D. A., Georgetti, S. R., Magro, D. A., Casagrande, R., Cunha, T. M., Vicentini, F. T., … & Verri Jr, W. A. (2009). Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production. Journal of Natural Products, 72(11), 1975-1979.

52-Shoskes, D. A., Zeitlin, S. I., Shahed, A., & Rajfer, J. (1999). Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology, 54(6), 960-963.